陳士林
陳士林，中國中醫科學院首席研究員，國際歐亞科學院院士，CGCM（中藥全球化聯盟）副主席、中國質量協會中藥分會會長；兼任香港浸會大學榮譽教授、日本東京藥科大學客座教授、教育部“長江學者和創新團隊計劃”創新團隊負責人等。曾任中國中醫科學院中藥研究所所長、中國醫學科學院藥用植物研究所所長、世界衛生組織傳統醫學合作中心主任， 香港理工大學客座教授，并在英國皇家植物園丘園接受專業培訓、哈佛醫學院Mclean醫院做訪問學者等?，F擔任APSB，Chinese Medicine，CHM，《藥學學報》等刊副主編。獲得第二屆全國創新爭先獎章。陳士林在國際上創建了基于ITS2的中草藥DNA條形碼鑒定方法體系，完成專著《中國藥典中藥材DNA條形碼標準序列》，從基因層面解決中草藥物種真偽鑒定的難題，被評為2016中國十大醫學進展；
通過全基因組解析提出靈芝為首個中藥基原藥用模式真菌，被Nature China 選為中國最佳研究亮點推介；完成并發表人參、丹參、赤芝、菊花、卷柏、穿心蓮、紫芝、紫蘇、黃連 等全基因組圖譜和相關組學研究，成功培育并獲批８個中藥材新品種證書或良種證書，主編并開拓創立《本草基因組學》學科并由科學出版社出版，列為全國高等醫藥院校規劃教材，奠定藥用植物分子遺傳學基礎；完成并編著《中國中藥材產地生態適宜性數值區劃》，避免中藥材盲目引種栽培，主持無公害種植項目成功推廣應用；
獲吳階平醫藥創新獎、Agilent Thought Leadership Award等榮譽；獲國家科技進步二等獎3項。獲國家發明專利和美國專利授權36項 ，發表論文500余篇，其中SCI論文300余篇，包括國際著名期刊Nature Communications，Mol Plant，PNAS等。連續六年入選Elsevier高被引中國學者榜單 。
近期主要論文：
1. Yujun Zhang,Qi Shen, Liang Leng, Dong Zhang, Sha Chen, Yuhua Shi, Zemin Ning & Shilin Chen Incipient diploidization of the medicinal plant Perilla within 10,000 years，Nature Communications volume 12, Article number: 5508 (2021)
2. Shilin Chen*.; Xu, J.; Liu, C.; Zhu, Y.; Nelson, D. R.; Zhou, S.; Li, C.; Wang, L.; Guo, X.; Sun, Y.; H Luo, Y Li, J Song, B Henrissat, A Levasseur, J Qian, J Li, X Luo, L Shi, LHe, L Xiang, X Xu, Y Niu, Q Li, Mira V. Han, H Yan, J Zhang, H Chen, A Lv, ZWang, M Liu, David C. Schwartz & C Sun*. Genome sequence of the model medicinal mushroom Ganoderma lucidum. Nature Communications 2012, 3, 913.
3. Liu, Y., Wang, B., Shu, Set al. Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids. Nature Communications 12,3276(2021). http://doi.org/10.1038/s41467-021-23611-0.
4. Chen S.*, Song, J., Sun, C., Xu, J., Zhu, Y., Verpoorte, R., Fan, T.-P*. Herbal genomics: Examining the biology of traditional medicines. Science 2015,347(6219),S27-S29 .
5. China Plant BOL Group, DZ Li et al., Comparative analysis of a large dataset indicates that internal transcribed spacer (ITS) should be incorportated into the core barcode for seed plants. PNAS, 2011,108:19641-19646.
6. Song, C; Liu, Y; Song, A; Dong, G; Zhao, H; Sun, W; Ramakrishnan, Shyam; Wang, Y; Wang, S; Li, T; Niu, Y; Jiang, J; Dong, B; Xia, Y; Chen, S; Hu, Z; Chen, F; Chen, Shilin, The Chrysanthemum nankingense genome provides insights into the evolution and diversification of chrysanthemum flowers and medicinal traits. Molecular plant, 2018 Vol: 11（12）: 1482-1491
7. Mengyue Guo、Xiaohui Pang、Yanqin Xu、Wenjun Jiang、Baosheng Liao、Jingsheng Yu、Jiang Xu、Jingyuan Song、Shilin Chen Plastid genome data provide new insights into the phylogeny and evolution of the genus Epimedium Journal of Advanced Research 2021
8. Xu J , Chu Y, Liao B, Xiao S, Yin Q, Bai R, Su H, Dong L, Li X, Qian J, Zhang J, Zhang Y, Zhang X, Wu M, Zhang J, Li G, Zhang L, Chang Z, Zhang Y, Jia Z, Liu Z, Daniel Afreh, Ruth Nahurira8, Zhang L, Cheng R, Zhu Y, Zhu G, Rao W, Zhou C, Qiao L, Huang Z, Cheng Yung-Chi, Chen Shilin, Panax ginseng genome examination for ginsenoside biosynthesis GigaScience 2017, 6(11):1-15.
9. Sun W; Leng L; Yin Q; Xu M; Huang M; Xu Z; Zhang Y; Yao H; Wang C; Xiong C; Jiang C; Xie N; Zheng X; Wang Y; Song C; Reuben J. Peters，Chen S;The medicinal plant Andrographispaniculate genome provides insight into biosynthesis of the bioactive diterpenoid neoandrographolide,Plant J 2018
10. Luo L, Jiang J, Wang C, Fitzgerald M, Hu W, Zhou Y, Zhang H, Chen S*. Analysis on herbal medicines utilized for treatment of COVID-19. APSB 2020(7), 10: 1192-1204.
11. Luo L, Dong L, Huang Q, Ma S, Fantke P, Li J, Jiang J, Fitzgerald M, Yang J, Jia Z, Zhang J, Wang H, Dai Y, Zhu G, Xing Z, Liang Y, Li M, Wei G, Song J, Wei J, Peng C, Zhang H, Zhang W, Wang S, Mizuno K, Marco A, Wu L, Xu J, Xiong C, Chen S*. Detection and risk assessments of multi-pesticides in 1771 cultivated herbal medicines by GC/MS-MS and LC/MS-MS. Chemosphere. 2021,262:127477.
12. Z Xu, T Xin, Dorothea Bartels,Y Li, W Gu,H Yao,S Liu,H Yu,X Pu, J Zhou, J Xu, C Xi ,H Lei Jingyuan Song,Shilin Chen.Genome analysis of the ancient tracheophyte Selaginella tamariscinareveals evolutionary features relevant to the acquisition of desiccation tolerance. Mol Plant 2018.
13. Xu, Z.; Peters, R. J.; Weirather, J.; Luo, H.; Liao, B.; Zhang, X.; Zhu, Y.; Ji, A.; Zhang, B.; Hu, S.; Au, K. F.; Song, J*.; Shilin Chen*., Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. The Plant Journal 2015.
14. Shilin Chen*.; Pang, X.; Song, J.; Shi, L.; Yao, H.; Han, J.; Leon, C., A renaissance in herbal medicine identification: from morphology to DNA.Biotechnology advances 2014, 32 (7), 1237-1244.
15. H Xu, J Song, H Luo, Y Zhang, Q Li, Y Zhu, J Xu, Y Li, C Song, B Wang, W Sun, G Shen, X Zhang, J Qian, A Ji, Z Xu, X Luo, L He, C Li, C Sun, H Yan, G Cui, X Li, Xi Li, J Wei, J Liu,Y Wang, A Hayward, D Nelson, Z Ning, RJ. Peters, X Qi, S Chen. Analysis of the Genome Sequence of the Medicinal Plant Salvia miltiorrhiza Mol Plant 2016, Volume 9, Issue 6, p949–952.
16. Zheng X, An W, Yao H, Xu J, Chen S*.Rapid authentification of the poisonous plant Gelsemium elegans by combining Filter-Paper-Based DNA extraction and RPA-LFD detection. Engineering 2021,7(1):14.16.
17. Li, X.; Yang, Y.; Henry, R. J.; Rossetto, M.; Wang, Y.; ShiLin Chen*, Plant DNA barcoding: from gene to genome. Biological Reviews 2015, 90 (1), 157-166.
18. Li, Q.; Li, Y.; Song, J.*; Xu, H.; Xu, J.; Zhu, Y.; Li, X.; Gao, H.; Dong, L.; Qian, J.; Sun, C, Shilin Chen*., High-accuracy de novo assembly and SNP detection of chloroplast genomes using a SMRT circular consensus sequencing strategy. New Phytologist 2014, 204 (4), 1041-1049.
19. LL Dong, J Xu ,Y Li,H Fang,W Niu,X Li,Y Zhang,W Ding,SL Chen, Manipulation of microbial community in the rhizosphere alleviates the replanting issues in Panax ginseng。Soil Biology and Biochemistry Volume 125, October 2018, Pages 64-74
20. R Shi, Z Hu, H Lu, L Liu, L Xu, Y Liu, H Wu, B Huang, G Zhang,* S Chen,* F Yang*, Hierarchical Nanostructuring Array Enhances Mid-Hybridization for Accurate Herbal Identification via ITS2 DNA Barcode. Analytical Chemistry, 2019, doi: 10.1021/acs.analchem.9b04687.
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